Dissecting Debakey's razor
Greg Purcell, Tanya Stewart
Royal North Shore Hospital, St. Leonards, NSW, Australia
William of Ockham, a small village in Surrey, became a celebrated Franciscan monk and philosopher, and initially published his dictum, since paraphrased "the simplest explanation is usually the best", that has been sharpened by subsequent philosophers and theologians to become the "Occam's razor" that tests simplicity on logical grounds.
Michael DeBakey pioneered surgical epistemology on aortic disruptions and confronted the razor in an unusual and contentious manner.
Managing acute thoracic aortic disruptions today has become more complex with the hasty administration of ADP receptor and cyclo-oxygenase inhibitors for severe cental chest pain.
Occram would benefit currently from the contributions of the University of Michigan's IRAD ( International Registry of Acute Aortic Dissections) and their insights lighten the journey however the ultimate destination remains elusive. Can we keep it simple?
- Lee R, Pybus DA. Transoesophageal Echocardiographic Evaluation Of Internal Mammary Artery Flow Pre- And Post-Coronary Artery Grafting. Heart, Lung and Circulation. 2007.16(1). S46-S47
- Hardman JG, Aitkenhead AR. Validation of an original mathematical model of CO2 elimination and dead space ventilation. Anesth Analg. 2003 Dec;97(6):1840-5.
- Pybus DA, Morris R, Jacobs J. A "virtual" blood gas electrode for use during cardiopulmonary bypass. J Extra Corpor Technol. 2007 Dec;39(4):311-2.
- Morris RW, Pybus DA. "Orpheus" cardiopulmonary bypass simulation system. J Extra Corpor Technol. 2007 Dec;39(4):228-33.
- Chalwin RP, Moran JL Graham Pl. The role of extracorporeal membrane oxygenation for treatment of adult respiratory distress syndrome. Anaes & Int. Care. 2008 Mar; 36(2): 152-161
- Smith M. Perioperative uses of transcranial perfusion monitoring. Anesthesiol Clin. 2007 Sep;25(3):557-77
- Mathews L, Singh KR. Cardiac output monitoring. Ann Card Anaesth. 2008 Jan-Jun;11(1):56-68.
- Platt MJ. Heads up display. Br J Anaesth. 2004 Apr;92(4):602-3.
- Ng JY, Man JC, Fels S, Dumont G, Ansermino JM. An evaluation of a vibro-tactile display prototype for physiological monitoring. Anesth Analg. 2005 Dec;101(6):1719-24.
- Hannan EL, Wu C, Walford G et al. Drug-eluting stents vs. coronary-artery bypass grafting in multivessel coronary disease. N Engl J Med. 2008 Jan 24;358(4):331-41.