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Acute Myocardial Ischaemia in the Presence of Thrombotic Thrombocytopenic Purpura: What Are the Treatment Options?

ABSTRACT

We describe a case of severe myocardial ischaemia in the setting of thrombotic thrombocytopoenic purpura (TTP). In this report, we discuss the potential difficulties in the diagnosis and management of acute myocardial ischaemia with TTP, particularly relating to the use of antiplatelet agents. We also highlight the importance of careful monitoring during plasma exchange for TTP when acute myocardial ischaemia is present. The potential role for novel therapies in the management of TTP related myocardial ischaemia is also discussed. (Critical Care and Resuscitation 2001; 3: 45-47)

Key words:

Thrombotic thrombocytopenic purpura, acute myocardial ischaemia, cardiac arrest

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