Hepatic and Renal Failure Associated with Amiodarone Infusion in a Patient with Hereditary Fructose Intolerance
ABSTRACT
Hereditary fructose intolerance is a rare inherited metabolic disorder. Although fructose intolerance usually presents in the paediatric age group, individuals can survive into adulthood by self-manipulation of diet. Hospitalisation can become a high-risk environment for these individuals because of loss of control of their strict dietary constraints and the added danger of administration of medications containing fructose, sucrose and sorbitol. We report a case of hereditary fructose intolerance in an adult presenting with hepatic and renal failure associated with an amiodarone infusion and explore the possibility of polysorbate 80 as a cause of this patient's hepatic and renal failure. (Critical Care and Resuscitation 2002; 4: 112-115)
Key words:
Hereditary fructose intolerance, hepatic failure, renal failure, polysorbate 80
