The Balanced Anaesthesia Study

The Balanced Anesthesia Study attracted a 2013 NHMRC grant of more than $2.8 million, as well as a grant of $1.2 million from the New Zealand Health Research Committee. This study also received funding from the ANZCA Research Foundation. The study is led by Associate professor Timothy Short in New Zealand, and Professor Kate Leslie in Australia. Other investigators are Professor Matthew Chan (HK), Clinical Professor Tomas Corcoran (WA), Professor Paul Myles (Vic), Professor Michael Paech.

The primary aim of this study is to determine the effect of light versus deep general anaesthesia on all-cause mortality at one year post-operatively in 6,500 moderate to high risk patients having major non-cardiac surgery.

Secondary outcomes include awareness, myocardial infarction, cardiac failure, stroke, pulmonary embolism, deep venous thrombosis, pneumonia, sepsis, wound infection, renal/liver dysfunction, patient satisfaction, cancer recurrence and persistent post-operative pain.

Patients will be enrolled from approximately 70 sites worldwide over a 4 year period with 1-year follow-up for the primary outcome.


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