Publications and grant outcomes


Publications arising from ANZCA funded research grants:




Abdelhamid YA, Cousins CE, Sim JA, Bellon MS, Nguyen NQ, Horowitz M, Chapman MJ, Deane AM. Effect of Critical Illness on Triglyceride Absorption.  J Parenter Enteral Nutr, 2015;39:966-972.


Allen M, Leslie K, Hebbard G, Jones I, Mettho T, Maruff P.  A randomized controlled trial of light versus deep propofol sedation for elective outpatient colonscopy: recall, procedural conditions, and recovery.  Can J Anesth 2015;62:1169-1178.

Afsharimani B, Doornebal C, Cabot PJ, MW. Hollmann, MO. Parat. Comparison and analysis of the animal models used to study the effect of morphine on tumour growth and metastasis. Br. J. Pharmacol., 2015;172(2):251-9.


Barrington MJ, Uda Y, Pattullo SJ, Sites BD Wrong Site Regional Anesthesia: Review and Recommendations for Prevention Curr Opin Anaesthesiol 2015 (Accepted for publication, August 2015).


Brull R, Hadzic A, Reina MA, Barrington MJ: Pathophysiology and Etiology of Nerve Injury Following Peripheral Nerve Blockade. Reg Anesth Pain Med 2015;40:479-490


Davidson AJ, Morton NS, Arnup SJ, et al. Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study: Comparing Apnea and Neurodevelopmental Outcomes, A Randomized Controlled Trial. Anesthesiology. 2015;123:38-54

Devcich DA, Weller J, Mitchell SJ, McLaughlin S, Barker L, Rudolph JW, Raemer DB, Zammert M, Singer SJ, Torrie S, Frampton CMA, Merry AF.  A behaviourally anchored rating scale for evaluating the use of the WHO surgical safety checklist:  development and initial evaluation of the WHOBARS.  BMJ Qual Saf, 2015.  First published online November 20, 2015. Doi:10.1136/bmjqs-2015-004448. 


Frawley G, Bell G, Disma N, Withington DE, de Graaff JC, Morton NS, McCann ME, Arnup SJ, Bagshaw O, Wolfler A, Bellinger D, Davidson AJ.  Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair Data from the General Anesthesia Compared to Spinal Anesthesia (GAS) Study: Comparing Apnoea and Neurodevelopmental Outcomes. Anesthesiology. 2015;123:55-65


Hiller JG, Parat M-O, Ben-Eliyahu S.  The role of perioperative pharmacological adjuncts in cancer outcomes: beta-adrenergic receptor antagonists, NSAIDs and antifibrino­ly­tics. Current Anesthesiology Reports – Onco-Anesthesia Edition (2015) Vol 5, Issue 3. DOI 10.1007/s40140-015-0113-x Invited review


Ho KM, Duff OC. Predictors of increased in-vitro thrombotic and bleeding tendency in critically ill trauma and non-trauma patients. Anaesthesia & Intensive Care 2015;43:317-322


Johnson L, Tan S, Hyland R, Reade MC, Marks D. In vitro comparison of cryopreserved and liquid platelets: potential clinical implications. Transfusion 2015;55:838-847.


Khabbazi S, Goumon Y, Parat M-O. Morphine modulates IL-4- or breast cancer cell-induced pro-metastatic activation of macrophages. Sci. Rep. 2015;5:11389.

Leslie K, Myles P, Forbes A, Chan, M, , Peyton P, Paech M, Sessler D, Devereaux PJ.  Nitrous oxide and serious long-term morbidity and mortality in the evaluation of nitrous oxide in the gas mixture for anaesthesia (ENIGMA)-II trial.  Anesthesiology.  2015;123:1267-80. 


Maddison KJ, Shepherd KL, Baker VA, Lawther B, Platt P, Hillman DR, Eastwood PR, Walsh JH. Effects on upper airway collapsibility of presence of a pharyngeal catheter. J Sleep Res 2015;24:92-99.


McNab S, Duke T, South M, Babl FE, Lee KJ, Arnup SJ, Young S, Turner H, Davidson A. 140 mmol/L of sodium versus 77 mmol/L of sodium in maintenance intravenous fluid therapy for children in hospital (PIMS): a randomised controlled double-blind trial. The Lancet. 2015;385:1190-7.


Neal JM, Barrington MJ, Brull R, Hadzic A, Hebl JR, Horlocker TT, Huntoon MA, Kopp SL Rathmell JP, Watson J C The Second ASRA Practice Advisory on Neurologic Complications Associated With Regional Anesthesia and Pain Medicine: Executive Summary 2015. Reg Anesth Pain Med 2015;40:401-430.


Paech M, Sng B, Ng L, Nathan E, Sia A, Carvalho B. Methylnaltrexone to prevent intrathecal morphine-induced pruritus after caesarean delivery: A multicentre, randomised clinical trial. Br J Anaesth.  2015;114:469-76. 


Saxena MK, Taylor C, Billot L, Bompoint S, Gowardman J, Roberts JA, Lipman J, Myburgh J. The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PLOS ONE. DOI:10.1371/journal.pone.0144740. December 17, 2015.

Shulman MA, Myles PS, Chan MTV, McIlroy DR, Wallace S, Ponsford J. Measurement of disability-free survival after surgery. Anesthesiology 2015;122:524-36.


Van Zyl N, Reade MC, Fraser JF. Experimental models of traumatic coagulopathy: a systematic review. Shock 2015;44:16-24.


Xie N, Parat M-O. Opioid analgesic agents and cancer cell biology. Current Anesthesiology Reports – Onco-Anesthesia Edition (2015) Vol 5, Issue 3. DOI 10.1007/s40140-015-0118-5.



Chow CK, Chan MTV, Halliwell R. Smoking and perioperative cardiovascular and medical outcomes in patients undergoing non-cardiac surgery. Presented at the World Congress of Cardiology 2014 May 4-7, Melbourne, abstract published as GHeart 2014; 9: e16-17


Dumont LJ, Slichter SJ, Reade MC. Cryopreserved platelets – Frozen in a log-jam? Transfusion, 2014; 54: 1907-1910.


Drummond PD, Drummond ES, Dawson LF, Mitchell V, Finch PM, Vaughan CW, Phillips JK. Up-regulation of α1-adrenoceptors on cutaneous nerve fibres after partial sciatic nerve ligation and in complex regional pain syndrome type II. Pain 2014;155:606-616.


Drummond PD. Invited review: Neuronal changes resulting in up-regulation of alpha-1 adrenoceptors after peripheral nerve injury. Neural Regeneration Research 2014;9:1337-1340.


Finch PM, Drummond ES, Dawson LF, Phillips JK, Drummond PD. Up-regulation of cutaneous a1-adrenoceptors in complex regional pain syndrome type I. Pain Medicine 2014;15:1945-1956.


Gustin SM, Wrigley PJ, Youssef AM, McIndoe L, Wilcox SL, Rae CD, Edden R, Siddall PJ, Henderson LA.  Thalamic activity and biochemical changes in individuals with neuropathic pain following spinal cord injury.  Pain, 2014;155:1027-1036.


Ironfield CM, Barrington MJ, Kluger R, Sites B.  Are patients satisfied after peripheral nerve blockade? Results from an International Registry of Regional Anesthesia.  Regional Anesthesia and Pain Medicine 2014;39(1):48-55.


Law CJ, Jacobson GM, Kluger M, Chaddock M, Scott M, Sleigh JW.  Randomized controlled trial of the effect of depth of anaesthesia on postoperative pain.  Br J Anaesth, 2014;112:675-680.


Lin E, Snell GI, Levvey BJ, Mifsud N, Paul M, Buckland MR, Gooi J, Marasco S, Sharland AF, Myles PS. Safety, feasibility and effect of remote ischemic conditioning in patients undergoing lung transplantation.  Journal of Heart Lung Transplant 2014;33(11):1139-1148.


McIlroy DR, Chan MTV, Wallace SK, Symons JA, Loo EGY, Chu LCY, Myles PS.  Automated preoperative assessment of endothelial dysfunction and risk stratification for perioperative myocardial injury in patients undergoing non-cardiac surgery.  Br J Anaesth 2014;112(1):47-56.


Milford EM, Tung JP, Reade MC. The need for a definitive clinical trial of cryopreserved red blood cells. Journal of Trauma and Acute Care Surgery, 2014; 77(6): 1004.


Myles PS,  Leslie K, Chan MTV, Forbes A, Peyton P, Paech MJ, Beattie S, Sessler DI, Devereaux PJ, Silbert B, Shricker T, Wallace S, and the ANZCA Trials Group for the ENIGMA-II investigators.  The safety of additional nitrous oxide to general anaesthesia at-risk patients having non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial.  The Lancet, 2014;384:1446-1454.


Roesl C, Sato K, Schiemann A, Pollock N, Stowell KM. Functional characterization of the R2452W ryanodine receptor variant associated with malignant hyperthermia susceptibility. Cell Calcium 2014;56(3):195-201.


Schiemann A.H, Paul N, Parker R, Pollock N, Bulger TF, Stowell KM. Functional characterization of two known ryanodine receptor mutations causing Malignant Hyperthermia (2014).  Anesthesia & Analgesia: 2014;118(2):375-380.


Stowell, K M DNA Testing for Malignant Hyperthermia: The Reality and the Dream. Anesthesia and Analgesia 2014;118(2):397-406.


Weinberg L, Pearce B, Sullivan R, Siu L, Scurrah N, Tan C, Backtrom M, Nikfarjam M, McNicol L, Story D, Christophi C, Bellomo R. The effects of plasmalyte-148 versus hartmann's solution during major liver resection: a multicentre, double-blind, randomized controlled trial. Minerva Anesthesiol. 2014 Nov 19. EPub ahead of print.


Weller J, Torrie J, Boyd M et al, Improving team information sharing with a structure call-out in anaesthetic emergencies: a randomized controlled trial. Br J Anaesth, 2014;112(6):1042-9. 


Weller JM, Henderson R, Webster C, Shulruf B, Torrie J, Davies E, Henderson K, Frampton C, Merry AF.  Building the Evidence on Simulation Validity: Comparison of Anesthesiologists' Communication Patterns in Real and Simulated Cases. Anesthesiology 2014;120:142-8.


Weller JM,  Henning M, Civil N, La very L, Boyd MJ, Jolly B. Approaches to learning for the ANZCA Final Examination and validation of the revised Study Process Questionnaire in specialist medical training, Anaesth Intensive Care 2013;41:631-640.



Barrington MJ, Kluger R.  Ultrasound guidance reduces the risk of local anesthetic systemic toxicity following peripheral nerve blockade. Regional Anesthesia and Pain Medicine, 2013;38(4):289-297.


Belavy D, Wallis SC.  Propylene glycol and glycerol concentration in ultrasound gel. Reg Anesth Pain Med 2013;38:75-76.


Belavy D et al, Absence of neurotoxicity with perineural injection of ultrasound gels: assessment using an animal model. BMC Anesthesiol 2013;13:18.


Callaway J.K., Jones NC, Royse CF. Reply to: Isoflurane is not necessarily the only cause of cognitive deficits. Eur. J. Anaesthesiol. 2013;30:43-44.


Chen YC, Liu XL, Cheng CHK, Gin T, Leslie K, Myles PS, Chan MTV.  Leukocyte DNA damage and wound infection after nitrous oxide administration: a randomized controlled trial.  Anesthesiology.  2013;118:1322-31.


Cowie B, Kluger R, Kalpokas M.  Left ventricular volume and ejection fraction assessment with transoesophageal echocardiography: 2D vs 3D imaging.  Br J Anaesth. 2013;110(2):201-06.

Hannam JA, Glass L, Kwon J, Windsor J, Stapelberg F, Callaghan K, Merry AF, Mitchell SJ.  A prospective, observational study of the effects of implementation strategy on compliance with a surgical safety checklist.  BMJ Qual Saf 2013;22:11 940-947.


Gin T, Liu XD, Lu N, Tian YY, Cheng CHK, Chan MTV. STAT3 Contributed to Mechanical Allodynia by Regulating Chemokine Expression in Astrocytes. Anesthesiology, 2013: A1091


Holley AD, Marks D, Johnson L, Reade MC, Badloe JF, Noorman F. Frozen blood products: clinically effective and potentially ideal for remote Australia. Anaesthesia and Intensive Care, 2013; 41(1): 10-19.


Liu XD, Tian YY, Lu N, Gin T, Cheng CHK, Chan MTV. Stat3 Inhibition attenuates mechanical allodynia through transcriptional regulation of chemokine expression in spinal astrocytes. PLoS ONE, 2013; 8: e75804.


Reade MC, Marks DC, Johnson L, Irving D, Holley AD. Frozen platelets for rural Australia: the CLIP trial. Anaesthesia and Intensive Care, 2013; 41(6): 804-805.


Sato K, Roesl C, Pollock N, Stowell K. Skeletal Muscle Ryanodine Receptor Mutations Associated with Malignant Hyperthermia Showed Enhanced Intensity and Sensitivity to Triggering Drugs When Expressed in HEK-293T Cells.  Anesthesiology.  2013;119(1):111-118.

Shekar K, Roberts JA, Ghassabian S, Mullany DV, Wallis SC, Smith MT, Fraser JF.  J Antimicrob Chemother, 2013;doi:10.1093/jac/dks435.


Story DA, Lees L, Weinberg L, Teoh SY, Lee KJ, Velissaris S, Bellomo R, Wilson SJ. Cognitive changes after saline or plasmalyte infusion in healthy volunteers. A multiple blinded, randomized, cross-over trial.  Anesthesiology, 2013;119:569-75.


Weatherall A, Garner A, Lovell N, Redmond S, Lee A, Skowno J, Egan J. Study protocol for the PHANTOM study: prehospital assessment of noninvasive tissue oximetry monitoring. Scand J Trauma, Resusc Emerg Med. 2014;22:57.


Weller J, Shulruf B, Torrie J, Frengley R, Boyd M, Paul A, et al. Validation of a measurement tool for self-assessment of teamwork in intensive care. Br J Anaesth.  2013;111(3): 460-7. 


Weller JM, Torrie J, Henderson R. The validity of simulation for team training for patient safety in anaesthesia: an observational study comparing team interactions in the operating room and the simulated environment. (Abstract WCA Paris 2012, paper 249) Br J Anaesth 2013;108: 316-317.



Callaway JK, Jones NC,Royse AG, Royse CF. Sevoflurane anesthesia does not impair acquisition learning or memory in the Morris water maze in young adult and aged rats. Anesthesiology 2012;117:1-­‐11.


Canty D, Royse C, Kilpatrick D, Bowman L, Royse A. The impact of focused transthoracic echocardiography in the pre-operative clinic. Anaesthesia 2012; 67(6): 618-25. 


Canty D, Royse C, Kilpatrick D, Williams D, Royse A.The impact of preoperative focused transthoracic echocardiography in emergency non-cardiac surgery patients with known or risk of cardiac disease. Anaesthesia 2012; 67(7): 714-20. 


Royse CF, Canty DJ, et al. Core review: physician-performed ultrasound: the time has come for routine use in acute care medicine. Anesthesia & Analgesia 2012;115(5):1007-28.


Canty D, Royse C, Kilpatrick D, Bowyer A, Royse A.The impact on cardiac diagnosis and mortality of focused transthoracic echocardiography in hip fracture surgery patients with increased risk of cardiac disease: a retrospective cohort study. Anaesthesia 2012;67(11):1202-9.  

Konstantatos A, Chan MTV et al.  A prospective cohort study comparing early opioid requirement between Chinese from Hong Kong and Caucasian Australians after major abdominal surgery.  Br J Anaesth 2012;109:797-803. 

Shekar K, Roberts JA, Mcdonald CI, Fisquet S, Barnett AG, Mullany DV, Ghassabian S, Wallis SC, Fung YL, Smith MT, Fraser JF.  Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care. 2012;16:R194.


Wong J, Lam DPL, Abrishami A, Chan MTV, Chung F. Short-term preoperative smoking cessation and postoperative complications: A systematic review and meta-analysis. Can J Anesth 2012; 59:268-79.



Dawson LF, Phillips JK, Finch PM, Inglis JJ, Drummond PD.  Expression of alpha1-adrenoceptors on peripheral nociceptive neurons.  Neuroscience, 2011;175:300-314.


Houliston B, Parry D, Mery AF. TADAA: Towards Automated Detection of Anaesthetic Activity. Methods of Information in Medicine 2011;50(5):464.


Phan T, Kluger R, Wan C, Wong D, Padayachee A.  A comparison of three minimally invasive cardiac output devices with thermodilution in elective cardiac surgery.  Anaesthesia and Intensive Care. 2011;39(6):1014-1021.


Vogts N, Hannam J, Merry AF, Mitchell SJ.  Compliance and quality in administration of a surgical safety checklist in a New Zealand hospital.  NZ Med J 2011;124(1342):48-58.


Law C, Jacobson G, Sleigh J, Barnard J.  Do single nucleotide polymorphisms predict morphine analgesia requirements in the immediate postoperative period? F1000 presentation based on 3rd World Congress of Total Intravenous Anaesthesia & Target Controlled Infusion (TIVA-TCI), 2011; 352.


Law CJ, Sleigh JW, Barnard JP, MacColl JN.  The association between intraoperative electroencephalogram-based measures and pain severity in the post-anaesthesia care unit.  Anaesth Intensive Care. 2011 Sep;39(5):875-80.


Leslie K, Myles PS, Chan MTV, Forbes A, Paech MJ, Peyton P, Silbert BS, Williamson E.  Nitrous oxide and long-term morbidity and mortality in the ENIGMA trial.  Anesth Analg 2011;112:387-93.


Merry AF, Webster CS, Hannam J, Mitchell SJ, Henderson R, Reid P, et al. Multimodal system designed to reduce errors in recording and administration of drugs in anaesthesia: prospective randomised clinical evaluation. BMJ. 2011;343. 


Merry AF, Wheeler DW.  Safety in medical simulation-overlooked or underappreciated? Can J Anaesth 2011;58(9):789-91.



Cumin D, Weller J, Henderson K, Merry AF. Standards for simulation in anaesthesia: creating confidence in the tool. Br J Anaesth 2010;105(1):45.

Greenland KB, Edwards MJ, Hutton NJ, Challis VJ, Irwin MG, Sleigh JW.  Changes in airway configuration with different head and neck positions using magnetic resonance imaging of normal airways: a new concept with possible clinical applications.  Br J Anaesth, 2010;105(5):683-90.


Griffiths JD, Middle JV, Barron FA, Grant SJ, Popham PA, Royse CF.  Transversus abdominis plane block does not provide additional benefit to multimodal analgesia in gynaecological cancer surgery.  Anesth Analg, 2010;111(3):797-801


Story DA, Leslie K, Myles PS, Fink M, Poustie SJ, Forbes A, Yap S, Beavis V, Kerridge R.  Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study.  Anaesthesia, 2010;65:1022-1030.


Royse CF, Newman S, Chung F, Stygall J, McKay RE, Boldt J et al. Development and feasibility of a scale to assess postoperative recovery: the post-operative quality recovery scale. Anesthesiology 2010;113:892-905.

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