The MASTER Trial

Multicentre Australian STudy of Epidural anaesthesia. The ANZCA Trials Group are the custodians of the MASTER Trial database. The Multicentre Australian Study of Epidural Anaesthesia and Analgesia in Major Surgery, the MASTER Trial, is a large, multi-centre, randomised clinical trial which evaluated the effect of epidural anaesthesia and postoperative epidural analgesia on postoperative morbidity and mortality in high risk surgical patients. The trial began in 1995 and was completed in 2001. The MASTER Trial was funded by the National Health and Medical Research Council of Australia, Health Department of Western Australia and The Australian and New Zealand College of Anaesthetists. The MASTER Trial was originally co-ordinated by the Department of Public Health, University of Western Australia.

For access to the MASTER Trial database, please fill in the data request application

and send it to the Trials Group Research Coordinators.

 

 

 Design of the Multicenter Australian Study of Epidural Anesthesia and Analgesia in Major Surgery: The MASTER Trial

Controlled Clinical Trials, Volume 21, Issue 3, June 2000, Pages 244-256
John R. A. Rigg JRA, Konrad Jamrozik, Paul S. Myles, Brendan Silbert, Philip Peyton, Richard W. Parsons, Karen Collins, for the MASTER Trial Study Group.

 

 

Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial

 The Lancet, Volume 359, Issue 9314, 13 April 2002, Pages 1276-1282
John RA Rigg, Konrad Jamrozik, Paul S Myles, Brendan S Silbert, Phillip J Peyton, Richard W Parsons, Karen S Collins and for the MASTER Anaesthesia Trial Study Group

 

 

Epidural anaesthesia and analgesia in major surgery

The Lancet, Volume 360, Issue 9332, 17 August 2002, Page 569
John Rigg, Konrad Jamrozik, Paul Myles, Brendan Silbert, Phil Peyton