| Dr Luke Perry | The Pulmonary Artery Catheters in Adults Undergoing Low-Risk Cardiac Surgery (PUMA) master protocol | 2026 |
| Professor Robert Sanders (NSW) | DECIDE study: Dexmedetomidine in Cardiac surgical Intraoperative Drug Evaluation | 2023 |
| Dr Daniel Frei (NZ) | Perioperative Medicine Platform trial (PROMPT) master protocol | 2025 |
| Professor Robert Sanders (NSW) | DECIDE study: Dexmedetomidine in Cardiac surgical Intraoperative Drug Evaluation | 2023 |
| Dr Luke Perry (Vic) | Pulmonary catheters in adults undergoing low risk cardiac surgery (The PUMA Pilot): a multicentre, randomised, controlled, consumer co-designed, Vanguard, pilot and feasibility clinical trial | 2023 |
| Professor David Sturgess and Dr Judy Munday (QLD) | The Glow Trial: Implementing Guidelines for hypothermia prevention with Local adaptation to keep periOperative patients Warm | 2023 |
| Dr Daniel Frei (NZ) | The HOT-ROX trial: The Hospital Operating Theatre- Randomised OXygen trial | 2022 |
| Professor Trisha Peel (Vic) | CALIPSO trial: The Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study | 2022 |
| Professor Kate Leslie (AO) (Vic) | The SNAPP study: Suggamedex, Neostigimine and Postoperative Pulmonary Complications | 2020 |
| Dr Benjamin Moran (NSW) | The PAIN-ICU Study: PAIN in Survivors of Intensive Care Units. A prospective, multi-centre observational Cohort study to determine the incidence, risk factors and impact of chronic pain in critically ill adult patients discharged from ICU | 2020 |
| Professor Paul Myles (Vic) | Prevalence of Asymptomatic SARS-Cov-2 Infection in Elective Surgical Patients in Australia: a prospective cohort study. | 2020 |
| Dr Raymond Hu (Vic) | TRICS IV trial: Restrictive versus Liberal Transfusion in Younger Patients Undergoing Cardiac Surgery. | 2019 |
Associate Professor Susan Humphreys (Qld) | HAMSTER trial: High-flow oxygen for children’s airway surgery: A randomised controlled trial. | 2019 |
Professor Paul Myles (Vic) | DECS-II trial: Comparative effectiveness of dexamethasone for cardiac surgery | 2019 |
| Professor Michael Reade (QLD) | CLIP-II: Cryopreserved vs. Liquid Platelets trial | 2018 |
| Professor Paul Myles (Vic) | TRIGS trial: Tranexamic acid to Reduce Infection after Gastrointestinal Surgery | 2018 |
| Dr Thomas Painter (SA) | POISE-3 Trial: PeriOperative ISchemic Evaluation-3 | 2018 |
| Professor Tomás Corcoran (WA) | LOLIPOP: Lidocaine and chronic post-surgical pain in breast cancer surgery | 2018 |
| Professor Bernhard Riedel (Vic) | VAPOR-C Study: Volatile Anaesthesia and Perioperative Outcomes Related to Cancer | 2018 |
| Associate Professor Gordon Doig (NSW) | Intravenous amino acid therapy for kidney protection in cardiac surgery patients: a multicentre randomised controlled trial.” | 2018 |
| Dr Doug Campbell (NZ) | MASTERSTROKE: Management of Systolic blood pressure Thrombectomy by Endovascular Route for acute ischaemic STROKE | 2018 |
| Associate Professor David Canty (Vic) | ECHONOF III trial: A pragmatic multicentre randomised trial of focused cardiac ultrasound prior to surgery for hip fracture. | 2018 |
| Associate Professor Lachlan Miles (Vic) | NATO study: Non-Anaemic Iron Deficiency and Tranfusion Outcomes after Colorectal Cancer Surgery | 2018 |
| Associate Professor Jai Darvall (Vic) | Chewy: A randomised non-inferiority trial of chewing gum versus ondansetron to treat postoperative nausea and vomiting in female patients after breast and laparoscopic surgery. | 2016 |
| Professor Yahya Shehabi (Vic) | Perioperative Dexmedetomidine in High Risk Cardiac Surgery Evaluation - DiCE II Trial; Muliticenter Multinational Randomised Double-Blind Placebo Controlled Trial. | 2017 |
| Dr Ianthe Boden (Tas) | CHESTY: (CHEST infection prevalence following surgerY) – an international multicenter observational trial. | 2017 |
| Professor Guy Ludbrook (SA) | Advanced Recovery Care | 2017 |
| Dr Nico Terblance (Tas) | PADDI-Hypothalamus Pituitary Adrenal Axis Sub-Study. | 2017 |
| Professor Philip Peyton (Vic) | ROCKet Study: Reduction Of Chronic Post-surgical Pain with Ketamine | 2016 |
| Professor Andrew Davidson (Vic) | T-REX Study: Neurodevelopmental outcome after sevoflurane versus dexmedetomidine/ remifentanil anaesthesia in infancy | 2016 |
| Professor Professor Yahya Shehabi (Vic) | DiCE 1: Dexmedetomidine in High Risk Cardiac Surgery Evaluation | 2016 |
| Professor Paul Myles (Vic) | ITACS Trial: IV iron for Treatment of Anaemia before Cardiac Surgery. | 2015 |
Professor Paul Myles (Vic) | EPICS-Australasia: Epidemiology of Critical care provision after Surgery | 2015 |
Dr Warren Pavey (WA) | Prothrombinex vs FFP for bleeding after cardiopulmonary bypass study | 2014 |
| Professor Alan Merry (NZ) | Z- bugs trial: Apprehending micro-organisms injected during anaesthesia. | 2014 |
| Professor David Story (Vic) | C-CaFe Trial: Colorectal cancer, anaemia and iron management | 2015 |
| Professor Paul Myles (Vic) | CELSUS trial: high-dose dexamethasone in cardiac surgery
| 2015 |
| Professor Tomás Corcoran (WA) | PADDI Trial: Perioperative ADministration of Dexamethasone and Infection trial | 2014 |
| Professor Paul Myles (Vic) | Statins Before Surgery Study 3S | 2014 |
| Dr Richard Halliwell (NSW) | International Surgical Outcomes Study (ISOS) | 2013 |
| Dr Doug Campbell (NZ) | NeuroVISION Study: Neurological impact of vascular events in noncardiac surgery patients cohort evaluation study. | 2013 |
| Dr Mark Shulman (Vic) | METS: Measurement of Exercise Tolerance for Surgery. | 2013 |